Flexible Small-Batch Filling & Closing Machine - (GENiSYS® c20)

Sterile Made Simple.Small Batch Filling & Closing Machine

GENiSYS® c20 is a compact combination filling system for automated aseptic processing of nested, ready-to-fill vials, syringes, and cartridges.  GENiSYS® c20 provides all the automated features of larger-scale filling systems in a compact footprint, making it ideal for use in flexible small scale filling applications, R&D process development, niche product manufacturing, clinical filling, and compounding pharmacies.

Advantages of Restricted Access Barrier System (RABS)

Along with designing filling machines for isolators to prevent contamination, we also offer machines that are used with RABS or Restricted Access Barrier System. Because isolators can have its drawbacks, such as making interventions more difficult, RABS offer an alternative that ensures a sterile environment and makes interventions a possibility.  

GENiSYS® c20 is designed for use within a Restricted Access Barrier System (RABS) or Laminar Air Flow (LAF) cabinet and ideal for labs and clean rooms with minimal available space.  AST’s meticulous attention to aseptic design, selection of the materials and surfaces has been done to ensure that the system meets cGMP standards for aseptic processing.

Applications include:

  • Clinical materials manufacturing
  • R&D and drug process development
  • Stability studies
  • Small batch commercial manufacturing
  • Compounding pharmacies
Technical Information

System Dimensions (LxWxH):

840mm x 500mm x 800mm [33" x 20" x 32"]


Vials, Syringes & Cartridges

Vial Finish:

13mm, 20mm, 32mm

Vials Sizes (Dia./Height):

Ø12mm-47mm / 35mm-100mm

Syringe Sizes:

0.5mL to 50mL

Cartridge Sizes:

1mL to 20mL

Other Container Options

Tooling for non-standard/custom container formats

Production Rate:

Up to 10 cycles per minute

Fill Accuracy:

Up to ±0.5%

Materials of Construction:

Pharmaceutical grade stainless steel, plastics, and elastomers

Human-Machine Interface (HMI)

ASTView on a 10" color touchscreen

Pump Options

Peristaltic & Rotary Piston

Available Options:

  • In-process fill weight verification (IPC)
  • Pre- and post-fill container closing with inert gas
  • Single-use disposable fluid paths
  • Product bag support stand
  • Isolator compatible system upgrade
  • Electronic Batch Report (EBR) System


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